Research Assistant - Automated Organic Synthesis Job at Stealth Startup, South San Francisco, CA

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  • Stealth Startup
  • South San Francisco, CA

Job Description

Team: Laboratory Automation & Operations

Company snapshot

We are revolutionizing organic chemistry with a fully automated synthesis platform. We combine high-throughput robotics and analytical technologies to accelerate small-molecule discovery.

What you'll do

  • Automated Synthesis Execution: Set up and run organic synthesis reactions using robotic liquid-handling systems, including sensitive reactions under inert conditions (glovebox, Schlenk lines) and photochemical reactions.
  • Robotic Work-Up Automation: Implement automated protocols for quenching, extraction, filtration, and evaporation (e.g., plate-based evaporators).
  • Stock Solution Preparation: Accurately weigh, dissolve, standardize, label, and organize reagent stock solutions and plates for robotic workflows.
  • Reagent Receipt & Qualification: Receive incoming chemical reagents and lab consumables, perform quality inspections, document batch information, and maintain inventory accuracy.
  • General Lab Maintenance: Manage shipping and receiving, maintain laboratory glassware and equipment, and perform routine upkeep to ensure seamless lab operations.
  • Data Management: Accurately document reaction parameters, analytical data (LC-MS, GC-MS), and reagent metadata in electronic lab notebooks, ensuring data integrity for AI/ML model development.
  • Instrument Maintenance: Regularly calibrate and maintain laboratory robotics, analytical instruments, and related equipment; troubleshoot technical issues as needed.
  • Protocol & Software Development: Assist in writing and refining Python or Bash scripts for automating laboratory workflows, data parsing, plate mapping, and instrument control.
  • Safety Compliance: Ensure adherence to chemical safety protocols, maintain accurate chemical inventories, and follow laboratory SOPs.

Minimum qualifications

  • B.S. or M.S. in Chemistry, Chemical Engineering, or related field.
  • 1+ year experience in an organic chemistry laboratory (industry or academia).
  • Familiarity with liquid-handling robots or analytical instrumentation.
  • Basic scripting proficiency (Python, Bash) or demonstrated ability to quickly acquire these skills.
  • Strong organizational skills with meticulous attention to detail.

Nice-to-have

  • Experience in high-throughput experimentation or automated reaction work-ups.
  • Knowledge of inert-atmosphere handling techniques (glovebox, Schlenk).
  • Experience with laboratory information management systems (LIMS) or similar data-management software.
  • Hands-on experience with spectroscopy and chromatography techniques.

What we offer

  • An exciting opportunity to contribute directly to groundbreaking automated chemical synthesis.
  • Close collaboration with company founders, synthetic chemists, and machine learning experts.
  • Competitive salary and comprehensive benefits.
  • A dynamic, innovative work environment where your contributions significantly advance scientific discovery.

Our company is an equal-opportunity employer.

Job Tags

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